Indicators on phenobarbital sodium obat apa You Should Know
Indicators on phenobarbital sodium obat apa You Should Know
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pentobarbital will reduce the level or effect of bexarotene by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lessen the extent or effect of budesonide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital will reduce the level or effect of duvelisib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. Coadministration with a powerful CYP3A inducer decreases duvelisib location underneath the curve (AUC), which can minimize duvelisib efficacy.
pentobarbital will lessen the level or effect of fentanyl transmucosal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Coadministration of fentanyl with CYP3A4 inducers could lead on into a decrease in fentanyl plasma concentrations, deficiency of efficacy or, probably, development of a withdrawal syndrome inside of a affected person who may have produced Bodily dependence to fentanyl.
1. Under the impact and appreciably impaired for uses of driving a motorcar or doing jobs necessitating alertness and unimpaired judgment and reaction time.
pentobarbital will minimize the extent or effect of ethinylestradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. The efficacy of hormonal contraceptives may be diminished. Utilization of a nonhormonal contraceptive is usually recommended.
pentobarbital will reduce the level or effect of conjugated estrogens, vaginal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will lessen the extent or effect of parecoxib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.
Fetal blood levels approach maternal blood concentrations pursuing parenteral administration. Withdrawal symptoms take place in infants born to mothers who receive barbiturates all through the final trimester of pregnancy. (See “Drug Abuse and Dependence” portion.) If this drug is used all through get more info pregnancy, or In case the affected person will become pregnant when taking this drug, the individual ought to be apprised in the potential hazard on the fetus.
pentobarbital will decrease the level or effect of efavirenz by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unknown.
Inspection: Parenteral drug goods should be inspected visually for particulate issue and discoloration before administration, Any time solution containers permit. Solutions for injection demonstrating evidence of precipitation shouldn't be used.
pentobarbital will lower the level or effect of lopinavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
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pentobarbital will decrease the extent or effect of dutasteride by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unfamiliar.